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    Contact Allergens


    Creative BioMart provides a comprehensive portfolio of recombinant contact allergens for skin sensitization research, patch testing, and in vitro diagnostic development. Our offerings include latex, microbial, plant, and animal-derived allergens, produced using advanced expression systems to ensure high purity, consistency, and reproducibility.

    Whether you are developing diagnostic assays, evaluating cosmetic safety, or studying allergic contact dermatitis, our contact allergen solutions support reliable and scalable research outcomes.

    Contact Allergen Product List

    Cat# Product Name Source Size Price Qty Inquiry
    RA-3694P Recombinant Hev b 13 E.coli or Yeast Inquiry
    RA-3695P Recombinant Hev b 15 E.coli or Yeast Inquiry
    RA-3931F Recombinant Tri r 2 E.coli or Yeast Inquiry
    RA-3932F Recombinant Tri r 4 E.coli or Yeast Inquiry
    RA-3933F Recombinant Tri t 1 E.coli or Yeast Inquiry
    RA-3934F Recombinant Tri t 4 E.coli or Yeast Inquiry
    RA-3960F Recombinant Mala f 2 E.coli or Yeast Inquiry
    RA-3961F Recombinant Mala f 3 E.coli or Yeast Inquiry
    RA-3962F Recombinant Mala f 4 E.coli or Yeast Inquiry
    RA-3963F Recombinant Mala s 1 E.coli or Yeast Inquiry
    RA-3964F Recombinant Mala s 5 E.coli or Yeast Inquiry
    RA-3965F Recombinant Mala s 6 E.coli or Yeast Inquiry
    RA-3966F Recombinant Mala s 7 E.coli or Yeast Inquiry
    RA-3967F Recombinant Mala s 8 E.coli or Yeast Inquiry
    RA-3968F Recombinant Mala s 9 E.coli or Yeast Inquiry
    RA-3969F Recombinant Mala s 10 E.coli or Yeast Inquiry
    RA-3970F Recombinant Mala s 11 E.coli or Yeast Inquiry
    RA-3971F Recombinant Mala s 12 E.coli or Yeast Inquiry
    RA-3972F Recombinant Mala s 13 E.coli or Yeast Inquiry

    What Are Contact Allergens?

    Contact allergens are substances that trigger immune responses when they come into direct contact with the skin. Unlike inhalant allergens that cause immediate IgE-mediated reactions, contact allergens typically induce delayed-type (Type IV) hypersensitivity reactions, leading to allergic contact dermatitis.

    These allergens are widely used in:

    • Skin sensitization studies
    • Patch testing
    • Cosmetic safety assessment
    • Occupational allergy research

    Common sources of contact allergens include proteins from latex, microorganisms, plants, animals, and chemical compounds found in industrial or cosmetic products.

    Contact allergens causing skin sensitization via Langerhans cells with latex, microbial, plant and animal allergen examples.Figure 1. Mechanisms of Contact Allergens and Skin Sensitization Pathways. (Creative BioMart)

    Types of Contact Allergens We Provide

    Creative BioMart offers a diverse selection of recombinant contact allergens, covering major allergen families relevant to dermatological and immunological research.

    Latex Allergens (Hev b Series)

    Latex allergens derived from Hevea brasiliensis are among the most clinically significant contact allergens, especially in healthcare and occupational settings.

    We provide a broad range of recombinant Hev b allergens (Hev b 1-15), supporting:

    • Latex allergy research
    • Occupational exposure studies
    • Diagnostic assay development

    Microbial & Fungal Allergens

    Microbial allergens, such as the Mala s series, are associated with skin conditions including atopic dermatitis and seborrheic dermatitis.

    These allergens are valuable for:

    • Skin microbiome-related allergy research
    • Chronic inflammatory skin disease studies

    Plant-Derived Contact Allergens

    Plant allergens such as Tri t (wheat), Tha p, and others play important roles in both environmental and occupational allergies.

    Applications include:

    • Agricultural exposure studies
    • Food-related skin sensitization research

    Animal-Derived Allergens

    Animal-derived allergens like Equ a and Equ c are commonly involved in occupational and environmental exposure.

    They are widely used in:

    • Veterinary and laboratory exposure studies
    • Allergy mechanism research

    Our products are available in multiple expression systems, including:

    • E. coli
    • Yeast
    • Cell-free systems

    Each product is optimized for research, diagnostic development, and industrial applications.

    Recombinant Contact Allergens vs Natural Extracts

    Compared with natural allergen extracts, recombinant contact allergens provide significant advantages:

    • High purity for precise experimental control
    • Batch-to-batch consistency for reproducibility
    • Defined molecular identity for diagnostic applications
    • Customizable formats, including labeled proteins (e.g., biotinylation)

    These features make recombinant allergens ideal for standardized assays, regulatory testing, and diagnostic development.

    Applications of Contact Allergens

    Our contact allergens are widely used across multiple research and industrial fields:

    • Patch Testing: Standardized allergens for evaluating allergic contact dermatitis in clinical and research settings.
    • In Vitro Diagnostics (ELISA, IgE/IgG Detection): Support development of sensitive and specific diagnostic assays.
    • Cosmetic Safety Evaluation: Assess skin sensitization potential of cosmetic ingredients and formulations.
    • Occupational Allergy Research: Study allergen exposure risks in healthcare, industrial, and agricultural environments.

    Why Choose Creative BioMart

    • Extensive allergen portfolio across multiple species and sources
    • Expertise in recombinant protein expression and purification
    • High-quality products with validated performance
    • Flexible customization and scalable production
    • Reliable support for research, diagnostics, and industrial development

    Custom Contact Allergen Services

    In addition to our standard catalog, Creative BioMart offers flexible customization services:

    • Custom allergen panels for specific applications
    • Protein labeling (e.g., biotin-labeled allergens)
    • Bulk production for industrial use
    • Tailored expression and purification strategies

    Our team works closely with clients to deliver application-specific allergen solutions.

    Frequently Asked Questions

    Q1: What is the difference between contact allergens and inhalant allergens?

    Q2: What allergens are used in patch testing?

    Q3: Why are recombinant allergens preferred?

    Q4: What are Hev b allergens?

    Q5: Can contact allergens be used in cosmetic testing?

    Q6: Do you provide custom allergen services?

    Looking for high-quality contact allergens for your research or diagnostic development? Creative BioMart offers reliable recombinant allergen solutions tailored to your application needs. Whether you require standard products or customized allergen panels, our team is ready to support your project. Contact us or request a quote today.

    For research or industrial raw materials, not for personal medical use.

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