Chironomus thummi thummi, commonly known as the Midge, harbors allergen proteins that can trigger allergic reactions in susceptible individuals. One such allergen, designated as Chi t 1 (Chironomus thummi thummi 1), belongs to the molecular family of midge allergens. These allergen proteins are characterized by their role in causing allergic responses, particularly in individuals exposed to midge infestations. Chi t 1 is a vital player in the allergenicity of midges and can be attributed to a range of allergic responses in affected individuals.
The biological functions of Midgeallergen proteins, such as Chi t 1, are closely tied to their allergenicity. These proteins serve as triggers for allergic reactions in individuals who come into contact with midges. When midge allergen proteins enter the human body, they interact with the immune system, often causing it to mount an allergic response. These responses can range from mild itching and skin irritation to more severe symptoms like hives, respiratory distress, or anaphylactic shock in severe cases.
The molecular mechanisms underlying midge-induced allergies involve the recognition of Chi t 1 by the immune system. Upon exposure, the immune system identifies Chi t 1 as a foreign invader, leading to the production of antibodies known as IgE. These antibodies bind to the allergen, triggering the release of histamines and other inflammatory mediators. This, in turn, leads to the classic allergic symptoms, such as itching, redness, and swelling.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3062A | Recombinant Chi k 10 | Chironomus kiiensis (Midge) | E.coli or Yeast | His |
| ra-3063A | Recombinant Chi t 1 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3064A | Recombinant Chi t 2 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3065A | Recombinant Chi t 3 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3066A | Recombinant Chi t 4 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3067A | Recombinant Chi t 5 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3068A | Recombinant Chi t 6 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3069A | Recombinant Chi t 7 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3070A | Recombinant Chi t 8 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3071A | Recombinant Chi t 9 | Chironomus thummi thummi (Midge) | E.coli or Yeast | His |
| ra-3163A | Recombinant For t 1 | Forcipomyia taiwana (Biting midge) | E.coli or Yeast | His |
| ra-3164A | Recombinant For t 2 | Forcipomyia taiwana (Biting midge) | E.coli or Yeast | His |
Midge allergen proteins, particularly Chi t 1, have opened doors to diagnostic and therapeutic advancements. Diagnostic tools have been developed to identify individuals sensitized to midge allergens. These tests help clinicians pinpoint allergies caused by midges, aiding in accurate diagnosis and treatment.
Furthermore, the study of midge allergen proteins like Chi t 1 has paved the way for potential vaccine development. Allergen-specific immunotherapy (AIT) is a promising approach aimed at desensitizing individuals allergic to midge proteins. By administering controlled doses of Chi t 1 or other midge allergens, the immune system can adapt and become less reactive over time. This can lead to a significant reduction in allergic symptoms upon future midge exposure.
Creative BioMart offers a comprehensive range of high-quality midge allergen-related protein products to support your research needs. Our extensive catalog includes a variety of Midge allergen proteins, allowing you to advance your studies in midge allergies, diagnostics, vaccine development, and allergy treatment. With our commitment to excellence in product quality and customer service, you can trust. Contact us and explore our extensive catalog today to find the midge allergen proteins that suit your specific requirements.
