Avocados, beloved for their creamy texture and nutritional value, are not universally adored. For some, consuming avocados can lead to allergic reactions. Avocado allergens are proteins found in avocados that trigger allergic reactions in susceptible individuals. These proteins belong to the Lipid Transfer Protein (LTP) family, a molecular group known for their involvement in allergic responses. The structural characteristics of Avocado allergen proteins vary, but they commonly exhibit a stable fold with a hydrophobic cavity, facilitating their interaction with lipids.
Avocado allergens are classified based on their molecular weights and sequence homology. Notably, the major allergen in avocados is known as Pers a 1, belonging to the Bet v 1-like protein family. This classification provides insights into the evolutionary relationships and potential cross-reactivity with other allergens.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3750P | Recombinant Pers a 1 | Persea americana (Avocado) | E.coli or Yeast | His |
The biological functions of avocado allergen proteins extend beyond the fruit's nutritional aspects. In individuals with avocado allergies, these proteins play a central role in triggering allergic responses. The molecular mechanisms underlying avocado allergy involve the recognition of specific epitopes on the allergen proteins by the immune system.
Avocado allergens contribute to allergic reactions by initiating an immune response that leads to the release of histamines and other inflammatory mediators. This, in turn, manifests as symptoms ranging from mild itching to severe anaphylaxis. Understanding the precise role of avocado allergen proteins in allergy is crucial for developing effective diagnostic tools and therapeutic interventions.
The molecular mechanisms underpinning avocado allergies are multi-faceted. Avocado allergen proteins possess unique structural features that make them particularly prone to triggering immune responses. The immune system identifies specific regions on these proteins as allergenic, initiating a hypersensitive reaction.
As allergen proteins interact with immune cells, particularly mast cells and basophils, a series of events unfold. This interaction triggers the release of preformed mediators like histamines and newly synthesized inflammatory compounds. The resulting allergic symptoms, ranging from skin rashes to gastrointestinal distress, underscore the diverse impact of avocado allergen proteins on the human body.
Explore the potential uses of avocado allergen proteins through Creative BioMart. Utilize state-of-the-art tools to make groundbreaking advancements in biomedicine. Contact us to browse our selection of avocado allergen proteins tailored to meet your requirements.
