Corn, a staple in diets worldwide, can sometimes be the source of allergic reactions due to specific proteins known as Corn allergens. These proteins trigger immune responses in susceptible individuals. Understanding Corn allergens involves delving into the molecular realm, where Zea m 1 and Zea m 8 take center stage.
Zea m 1 and Zea m 8 belong to the family of allergenic proteins found in corn. Zea m 1, a lipid transfer protein, plays a crucial role in the transport of lipids between cellular membranes. On the other hand, Zea m 8 is a profilin, involved in cytoskeleton dynamics. Both proteins exhibit unique structural characteristics that distinguish them within the corn genome. Corn allergens are classified based on their ability to induce allergic reactions. Class I allergens, including Zea m 1, are heat-resistant and stable, surviving various cooking processes. Class II allergens, exemplified by Zea m 8, are less stable and may be denatured during cooking, reducing their allergenic potential.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3501P | Recombinant Zea m 1 | Zea mays (Maize) | E.coli or Yeast | His |
| ra-3502P | Recombinant Zea m 8 | Zea mays (Maize) | E.coli or Yeast | His |
| ra-3503P | Recombinant Zea m 12 | Zea mays (Maize) | E.coli or Yeast | His |
| ra-3504P | Recombinant Zea m 14 | Zea mays (Maize) | E.coli or Yeast | His |
| ra-3505P | Recombinant Zea m 25 | Zea mays (Maize) | E.coli or Yeast | His |
Corn allergens play a pivotal role in corn allergy, which can manifest as skin reactions, gastrointestinal issues, respiratory distress, and even life-threatening anaphylaxis. Sensitization to Zea m 1 and Zea m 8 can occur through ingestion, inhalation, or skin contact with corn or corn-derived products.
The immune system identifies Corn allergens as foreign invaders, leading to the production of specific antibodies, such as IgE. Upon subsequent exposure, these antibodies trigger the release of histamines and other inflammatory substances, causing the allergic symptoms. The severity of the reaction varies among individuals, with some experiencing mild discomfort and others facing severe consequences.
The molecular mechanisms underlying corn allergies involve a complex interplay between the immune system and Corn allergen proteins. Upon exposure, the proteins are recognized by immune cells, initiating a cascade of events that result in the release of inflammatory mediators. This immune response is heightened in allergic individuals, leading to the manifestation of allergy symptoms.
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