Mugwort, scientifically known as Artemisia vulgaris, is not just a common herb in traditional medicine; it also harbors allergenic proteins that can trigger adverse reactions in sensitive individuals. In this article, we delve into the intricacies of Mugwort allergen proteins, focusing on Art la 1, Art la 2, and Art la 3.
Mugwort allergen proteins constitute a group of molecules within the molecular family of pathogenesis-related (PR) proteins. These proteins play a crucial role in the plant's defense mechanisms against pathogens. Art la 1, Art la 2, and Art la 3 are the primary allergenic proteins found in Mugwort.
Belonging to the PR-10 family, Mugwort allergen proteins share structural features with proteins involved in plant defense responses. The PR-10 family is characterized by a conserved fold known as the Bet v 1-like superfamily, which includes birch pollen allergen Bet v 1. This structural similarity contributes to the cross-reactivity observed between various plant allergens.
Art la 1, Art la 2, and Art la 3 are classified based on their distinct immunological properties. Art la 1, for instance, is a major allergen, while Art la 2 and Art la 3 contribute to the overall allergenicity of Mugwort. Understanding their classification is essential for deciphering the specific immune responses they elicit.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3984P | Recombinant Art la 1 | Artemisia lavandulifolia (Mugwort) | E.coli or Yeast | His |
| ra-3985P | Recombinant Art la 2 | Artemisia lavandulifolia (Mugwort) | E.coli or Yeast | His |
| ra-3986P | Recombinant Art la 3 | Artemisia lavandulifolia (Mugwort) | E.coli or Yeast | His |
Mugwort allergen proteins are notorious for their involvement in allergic reactions, particularly respiratory allergies such as hay fever. When sensitive individuals come into contact with Mugwort pollen, these proteins can trigger an immune response, leading to the release of histamines and other mediators that cause allergy symptoms.
The molecular mechanisms underlying Mugwort allergy involve the recognition of these allergenic proteins by the immune system. Art la 1, as a major allergen, is particularly adept at eliciting strong immune responses. Upon exposure, the proteins interact with specific receptors on immune cells, setting off a cascade of events that culminate in the manifestation of allergic symptoms.
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