Rabbit allergen proteins, collectively referred to as Ory c allergens, represent a complex array of allergenic molecules that have the potential to induce allergic responses in individuals who are predisposed to such reactions. These proteins are classified within the broader category of allergens, making them a significant subject of interest in the realm of allergic reactions. What sets these allergen proteins apart are their unique structural features, which play a pivotal role in their ability to trigger allergic responses. In the following sections, we will embark on an in-depth exploration of rabbit allergen proteins, delving into their intricate composition, biological functions, and their central role in the development of allergic conditions.
Rabbit allergen proteins encompass a range of molecules with varying degrees of allergenicity. Among the most notable are Ory c 1, Ory c 2, Ory c 3, and Ory c 4. Each of these allergens possesses unique structural features that contribute to their allergenic potential. Ory c 1, for instance, is a lipocalin protein, characterized by a β-barrel structure and the ability to bind small hydrophobic molecules. On the other hand, Ory c 2 is a serum albumin, while Ory c 3 and Ory c 4 belong to the IgE-binding protein family. These diverse structural characteristics underline the complexity of rabbit allergen proteins.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3371A | Recombinant Ory c 1 | Oryctolagus cuniculus (Rabbit) | E.coli or Yeast | His |
| ra-3372A | Recombinant Ory c 3 | Oryctolagus cuniculus (Rabbit) | Yeast | His |
| ra-3373A | Recombinant Ory c 4 | Oryctolagus cuniculus (Rabbit) | E.coli or Yeast | His |
The biological functions of rabbit allergen proteins are intertwined with their allergenic properties. When these proteins come into contact with the immune system of a susceptible individual, they can trigger an allergic response. This occurs because the immune system recognizes these proteins as foreign invaders and mounts an immune response against them. In individuals with a predisposition to allergies, such as asthma or rhinitis, this immune response can lead to the production of IgE antibodies specific to rabbit allergen proteins. Upon subsequent exposure, these antibodies bind to the allergens, setting off a cascade of events that result in the release of histamine and other inflammatory mediators. This, in turn, leads to the classic symptoms of allergy, including sneezing, itching, congestion, and in severe cases, anaphylaxis.
The molecular mechanisms underlying rabbit allergen-induced allergies are complex and multifaceted. When rabbit allergen proteins enter the body, they are processed by antigen-presenting cells and presented to T-helper cells. This interaction triggers the activation of B cells, leading to the production of IgE antibodies specific to the allergen. Upon re-exposure to the allergen, these IgE antibodies bind to mast cells and basophils, initiating the release of inflammatory mediators. This process is known as the immediate hypersensitivity reaction, and it is responsible for the rapid onset of allergy symptoms.
Rabbit allergen proteins play a crucial role in the development of diagnostic tools, vaccines, and treatments for allergies. In diagnostic development, specific IgE tests can identify individuals sensitized to rabbit allergens, aiding in the accurate diagnosis of allergies. Additionally, these proteins are used in the development of allergy vaccines, known as allergen immunotherapy. Allergen immunotherapy involves exposing individuals to gradually increasing doses of rabbit allergen proteins to desensitize their immune system and reduce allergic reactions over time. It is a long-term treatment option for managing allergies effectively.
Creative BioMart offers a comprehensive range of rabbit allergen-related protein products, catering to the diverse needs of researchers and professionals in the field. Our top-quality proteins are meticulously produced and rigorously tested to ensure reliability and consistency, making them invaluable tools for allergy research, diagnostic development, and therapeutic advancements. Contact us and explore our extensive catalog of rabbit allergen proteins today and unlock new possibilities in your work.
