Strawberries, with their vibrant red hue and succulent sweetness, are a beloved fruit enjoyed by many. However, for some individuals, consuming strawberries can lead to allergic reactions due to specific proteins found within the fruit. In this article, we will delve into the intricate world of Strawberry allergen proteins, exploring their composition, biological functions, and potential applications in biomedicine.
Strawberry allergens primarily consist of proteins that trigger allergic reactions in susceptible individuals. These proteins belong to the broader molecular family of pathogenesis-related (PR) proteins. Within this family, the allergens are classified as PR-10 proteins.
PR-10 proteins, including those found in strawberries, are characterized by their compact, globular structures. The molecular weight of Strawberry allergen proteins typically ranges from 17 to 18 kilodaltons. These proteins possess a distinctive three-dimensional arrangement, and their structures often involve binding sites for small ligands.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3665PB | Recombinant Fra a 1, Biotin Labeled | Strawberry | E.coli | His |
| ra-3665P | Recombinant Fra a 1 | Fragaria ananassa (Strawberry) | Yeast | His |
| ra-3666P | Recombinant Fra a 3 | Fragaria ananassa (Strawberry) | E.coli or Yeast | His |
| ra-3667P | Recombinant Fra a 4 | Fragaria ananassa (Strawberry) | E.coli or Yeast | His |
The biological functions of Strawberry allergen proteins extend beyond mere triggers of allergic reactions. These proteins play a role in the plant's defense mechanisms against pathogens. PR-10 proteins are part of the plant's immune response, acting as molecular sentinels that help the plant combat various environmental stresses, such as fungal infections.
For individuals with strawberry allergies, the immune system perceives specific proteins within the fruit as harmful invaders. The most common Strawberry allergen is known as Fra a 1, a PR-10 protein. When ingested, the immune system identifies Fra a 1 as a threat, leading to the production of antibodies, such as immunoglobulin E (IgE). The subsequent allergic reactions result from the release of histamines and other inflammatory mediators.
The molecular mechanisms underlying strawberry allergies involve the binding of IgE antibodies to the allergen, initiating a cascade of immune responses. This includes the release of histamines, which cause symptoms ranging from mild itching and hives to more severe reactions like anaphylaxis.
