Watermelon, a summer staple, can bring joy to many, but for some, it can be a source of allergic reactions. The culprits behind watermelon allergies are allergen proteins, with Citr l 2 being a notable player. Understanding the specifics of watermelon allergen proteins, including their molecular composition, family classification, and structural characteristics, is crucial for effective allergy management.
Watermelon allergen proteins, including Citr l 2, fall under the molecular umbrella of pathogenesis-related proteins (PR-10 family). These proteins, involved in plant defense mechanisms, possess unique structural characteristics that make them noteworthy allergens. Citr l 2, specifically, is a major allergen associated with watermelon allergies, and its classification within the PR-10 family guides research endeavors aimed at unraveling its role in allergic reactions.
| Cat.No. | Product Name | Species | Source | Tag |
| ra-3629P | Recombinant Citr l 2 | Citrullus lanatus (Watermelon) | E.coli or Yeast | His |
Watermelon allergen proteins, such as Citr l 2, serve dual purposes in the plant's life – defense mechanisms against pathogens and instigators of allergic reactions in certain individuals.
PR-10 proteins, including Citr l 2, are part of the plant's defense system. These proteins contribute to pathogen recognition and the activation of defense responses, protecting the plant from various threats. The biological functions in plants highlight the evolutionary significance of these proteins in ensuring the survival of watermelon plants in their natural environment.
The dark side of watermelon allergen proteins becomes evident when they encounter the immune system of allergic individuals. Citr l 2 and its counterparts contain specific epitopes that, when recognized by the immune system, trigger allergic reactions. The molecular mechanisms involve the binding of these epitopes to immune cells, leading to the release of histamines and other inflammatory mediators. This cascade of events manifests as the classic symptoms of allergies, ranging from mild itching to severe anaphylactic reactions.
